FÓRMULA REFORZADA CON ENDORPHYT €20,90

🌙 Melatonin

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  🎯 EU validated health claim (falling asleep): Melatonin helps reduce the time it takes to fall asleep. The beneficial effect is obtained by consuming 1 mg of melatonin before bedtime, in accordance with EU Regulation No. 432/2012.
  
  → Official EFSA source
  
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  🎯 EU health claim validated (jet lag): Melatonin helps mitigate the effects of jet lag. The beneficial effect is obtained by consuming at least 0.5 mg before bedtime on the first day of travel and the few days following the day of arrival at destination.
  
  → Official EFSA source
  
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  🧬 Natural hormone: melatonin is a hormone naturally produced by the pineal gland that regulates circadian rhythms in response to light variations.
  
  → Source PubMed (2017)
  
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  ⏰ Circadian rhythms: Melatonin plays a central role in synchronizing the internal biological clock with day-night cycles, a scientifically documented mechanism.
  
  → Source PubMed (2017)
  
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  🔬 Metabolism: Melatonin is metabolized mainly by the liver via the CYP1A2 enzyme, with a short half-life allowing natural sleep onset without residual drowsiness.
  
  → Source PubMed (2013)
  

🌿 Lemon balm (Melissa officinalis)

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  🧪 Phytochemical composition: lemon balm contains phenolic acids (rosmarinic acid, caffeic acid), flavonoids and essential oils rich in citral, citronellal and geranial.
  
  → Source PubMed (2010)
  
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  📚 Traditional use: Lemon balm has been used traditionally since Antiquity for its calming properties, mentioned by Avicenna and Paracelsus in their treatises on phytotherapy.
  
  → Source PubMed (2009)
  
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  🧠 Anxiety research: clinical studies have explored the effects of lemon balm on states of stress and anxiety, notably via rosmarinic acid.
  
  → Source PubMed (2003)
  
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  💤 Relaxing properties : Lemon balm extracts have been studied for their calming effects and ability to promote relaxation, particularly in interaction with GABA receptors.
  
  → Source PubMed (2009)
  
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  🌱 Soothing essential oils: Lemon balm essential oils, rich in monoterpenes, are studied for their aromatherapeutic properties and effect on relaxation.
  
  → Source PubMed (2014)
  
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  🔬 Standardization: standardized extracts of lemon balm guarantee a constant content of rosmarinic acid and phenolic compounds, ensuring reproducibility of the effects observed.
  
  → Source PubMed (2012)
  

🌜 Natural Sleep Synergy

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  🎯 Complementary approach: the melatonin-melissa combination combines the scientifically proven efficacy of the sleep hormone with the traditional relaxing properties of herbal medicine.
  
  → Source PubMed (2018)
  
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  🔄 Synergistic mechanisms: melatonin acts directly on circadian rhythms while lemon balm promotes relaxation through its phenolic compounds, offering a multimodal approach to sleep.
  
  → Source PubMed (2016)
  
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  ✨ Enhanced formula: this optimized combination allows you to benefit from the validated health claims of melatonin enriched by the traditional soothing properties of lemon balm.
  
  → Source PubMed (2017)
  
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  🌿 Falling asleep naturally: this combination respects the natural physiological processes of sleep by combining hormonal regulation and phytotherapeutic relaxation.
  
  → Source PubMed (2019)
  

⚠️ Important note: The above studies relate to melatonin and lemon balm as individual ingredients. These scientific data do not constitute a claim of efficacy for the finished product and are provided for information purposes only.